Sanify Healthcare Pvt. Ltd.

About Extractum Cepae Cepalin+heparin+allantoin

Extractum Cepae Cepalin+heparin+allantoin belongs to the group of medications called 'dermatological agents' primarily indicated for managing scars from surgery, burns, stretch marks, acne, and breast amputations. The scar is a brown or pale pink patch of skin that marks the site where the skin has healed.
Extractum Cepae Cepalin+heparin+allantoin should only be used externally.

Uses of Extractum Cepae Cepalin+heparin+allantoin

 

Treatment of scars

Additional Information:

• Item Code: SAVOSCAR-GEL
• Production Capacity: 2years
• Delivery Time: 3-4days
• Packaging Details: 20GM LAMI TUBE

Uses of AmorolfineTreatment of Fungal nail infection.Medicinal Benefits

Amorolfine is an antifungal that is primarily used to treat fungal infections of nails and skin such as ringworm, jock itch and athlete’s foot, seborrheic dermatitis (dry, flaky skin on face, scalp, chest, upper back, or ears) and pityriasis (a type of skin rash that causes scaly, discoloured patches on chest, back, legs and arms). The fungal cell membranes are essential for their survival as they prevent unwanted substances into the cells and stop the leakage of cell contents. Amorolfine causes holes in the fungal cell membranes and kills fungi. Thereby, clears fungal infection and provides relief from cracking, burning, scaling and itching of the skin caused due to infections. 

Additional Information:

• Item Code: Alamfine
• Production Capacity: 2years
• Delivery Time: 3-4days
• Packaging Details: 50g cream Tube pack

Polymyxin B was discovered in the 1940s5. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes4. Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic4,Label. All gram-positive bacteria, fungi, and the gram-negative cocci, are resistant4. It is appropriate for treatment of infections of the urinary tract, meninges, and blood stream, caused by susceptible strains of Pseudomonas aeruginosaLabel. Polymyxin B has a narrow therapeutic index and so its use is limited and unlikely to be used first line


The alpha and gamma diaminobutyric acid of a positively charged polymyxin B forms an electrostatic interaction with the phosphate groups of a negatively charged lipid A on the outer membrane of a Gram negative bacterium4. Calcium and Magnesium ions are displaced from phosphates of the membrane lipids, destabalising the lipopolysaccharide (LPS), increasing membrane permeability, causing cytoplasmic leaking, and killing the cell4.
Polymyxin B can also bind and neutralize LPS released during bacterial lysis, preventing reactions to endotoxin4.
A third activity of polymyxin B is the inhibition of type II NADH-quinone oxidoreductases in the bacterial inner membrane, which are essential for respiration4.
Polymyxin is active against common Gram negative bacteria but not Gram negative cocci, Gram positive bacteria, or anaerobic bacteria


Polymyxin B is proposed to be primarily eliminated through renal tubular reabsorption and non-renal pathways1. Urine collection in humans and animals show <5% of polymyxin B eliminated from the kidneys1. However, a Canadian product monograph states the drug is primarily eliminated through the kidneys and that 60% of polymyxin B is recovered in the urine. This discrepancy can be explained by the 12 to 24 hour lag time between administration and significant elimination of polymyxin B. Non-renal elimination is not well understood but all 4 components of polymyxin B have been detected in bile1.

^P_{olymyxin B injection is used to treat bacterial infections in many different parts of the body.}

_{Polymyxin B belongs to the group of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.}

_{This medicine is to be given only by or under the direct supervision of a doctor}

Additional Information:

• Item Code: Safycol-PB
• Delivery Time: 7 days
• Packaging Details: 5 ml Plastic Bottle